TRACHOMA (Greek: roughness) / MedUrgent
TRACHOMA (Greek: roughness)
Trachoma is a leading cause of blindness in the world. It is caused
by the bacteria Chlamydia trachomatis.
Pathogenesis:
Chlamydia trachomatis is spread by flies and fomites through wet secretions
from the eyes, nose and throat. A single attack may resolve spontaneously but
repeated attacks end up with entropion, corneal ulceration and complete
blindness.
Clinical
Incubation period is
5-7 days followed by conjunctival inflammation, appearance of conjunctival
follicles in the under surface of the upper eye lid and watery discharge that
may become purulent with secondary bacterial infection.
The condition is
associated with intense itching, eye discharge, photophobia and local
lymphadenopathy. Cicatricial trachoma is a late manifestation that includes
distortion of the eye lid (entropion), trichiasis (eye lid hair scratching the
cornea), corneal ulceration, scarring and blindness.
Treatment
-Azithromycin 20mg/kg once oral
-Topical tetracycline
ointment twice daily for 6 weeks
-Surgery
Prevention
-Facial cleanliness
-Environmental
sanitation and flies control
-Health education
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